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PPP1R13B Antibody

CAT: 0223-59-018Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-018Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
NCBI Gene ID
23368
Swiss Prot
Q96KQ4
Accession Number
Q96KQ4
Host
Rabbit
Reactivity
Human
Immunogen
This PPP1R13B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 623-652 amino acids from the Central region of human PPP1R13B.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
120 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP1R13B
NCBI Official Name
Apoptosis-stimulating of p53 protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Figl, A., et al. Mutat. Res. 702 (1) :8-16 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Zhao, J., et al. Hepatology 51 (1) :142-153 (2010)
Background Reference 04
Agirre, X., et al. Oncogene 25 (13) :1862-1870 (2006)
Other Product Names
Apoptosis-stimulating of p53 protein 1, Protein phosphatase 1 regulatory subunit 13B, PPP1R13B, ASPP1, KIAA0771
Tested Applications
WB
Protein ID
296439434
Physical Properties
Liquid

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