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PPP1R1C Antibody

CAT: 0223-60-075Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-60-075Size:400 µL
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Background
Protein phosphatase-1 (PP1) is a major serine/threonine phosphatase that regulates a variety of cellular functions. PP1 consists of a catalytic subunit (see PPP1CA; MIM 176875) and regulatory subunits that determine the subcellular localization of PP1 or regulate its function. PPP1R1C belongs to a group of PP1 inhibitory subunits that are themselves regulated by phosphorylation (Wang et al., 2008 [PubMed 18310074]) .[supplied by OMIM].
NCBI Gene ID
151242
Swiss Prot
Q8WVI7
Accession Number
Q8WVI7
Host
Rabbit
Reactivity
Mouse
Immunogen
This PPP1R1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 50-76 amino acids from the N-terminal region of human PPP1R1C.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
12 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPP1R1C
NCBI Official Name
Protein phosphatase 1 regulatory subunit 1C
NCBI Organism
Homo sapiens
Background Reference 01
Dick, D.M., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. (2010) In press :
Background Reference 02
Rose, J. Phd, et al. Mol. Med. (2010) In press :
Background Reference 03
Zeng, Q., et al. Biotechnol. Appl. Biochem. 54 (4) :231-238 (2009)
Background Reference 04
Wang, X., et al. J. Biol. Chem. 283 (18) :12076-12084 (2008)
Other Product Names
Protein phosphatase 1 regulatory subunit 1C, Inhibitor-5 of protein phosphatase 1, IPP5, PPP1R1C
Tested Applications
WB
Protein ID
74730857
Physical Properties
Liquid