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EDEM3 Antibody

CAT: 0223-58-568Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-568Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Quality control in the endoplasmic reticulum (ER) ensures that only properly folded proteins are retained in the cell through recognition and degradation of misfolded or unassembled proteins. EDEM3 belongs to a group of proteins that accelerate degradation of misfolded glycoproteins in the ER (Hirao et al., 2006 [PubMed 16431915]) .
NCBI Gene ID
80267
Swiss Prot
Q9BZQ6
Accession Number
Q9BZQ6
Host
Rabbit
Reactivity
Human
Immunogen
This EDEM3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 774-802 amino acids from the C-terminal region of human EDEM3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
105 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
EDEM3
NCBI Official Name
ER degradation-enhancing alpha-mannosidase-like protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Hirao, K., et al. J. Biol. Chem. 281 (14) :9650-9658 (2006)
Background Reference 02
Mast, S.W., et al. Glycobiology 15 (4) :421-436 (2005)
Background Reference 03
Olivari, S., et al. J. Biol. Chem. 280 (4) :2424-2428 (2005)
Background Reference 04
Sood, R., et al. Genomics 73 (2) :211-222 (2001)
Other Product Names
ER degradation-enhancing alpha-mannosidase-like protein 3, Alpha-1,2-mannosidase EDEM3, EDEM3, C1orf22
Tested Applications
WB
Protein ID
166897965
Physical Properties
Liquid

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