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DND1 Antibody

CAT: 0223-58-546Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-546Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.
NCBI Gene ID
373863
Swiss Prot
Q8IYX4
Accession Number
Q8IYX4
Host
Rabbit
Reactivity
Human
Immunogen
This DND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human DND1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
DND1
NCBI Official Name
Dead end protein homolog 1
NCBI Organism
Homo sapiens
Background Reference 01
Liu, X., et al. FEBS Lett. 584 (18) :4115-4120 (2010)
Background Reference 02
Sijmons, R.H., et al. Fam. Cancer 9 (3) :439-442 (2010)
Background Reference 03
Kedde, M., et al. Cell Cycle 7 (7) :899-903 (2008)
Background Reference 04
Linger, R., et al. Genes Chromosomes Cancer 47 (3) :247-252 (2008)
Other Product Names
Dead end protein homolog 1, RNA-binding motif, single-stranded-interacting protein 4, DND1, RBMS4
Tested Applications
WB
Protein ID
60389799
Physical Properties
Liquid

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