DND1 Antibody

• Background:

  This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.

• NCBI Gene ID:

  373863

• Swiss Prot:

  Q8IYX4

• Accession Number:

  Q8IYX4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human DND1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  39 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DND1

• NCBI Official Name:

  Dead end protein homolog 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Liu, X., et al. FEBS Lett. 584 (18) :4115-4120 (2010)

• Background Reference 02:

  Sijmons, R.H., et al. Fam. Cancer 9 (3) :439-442 (2010)

• Background Reference 03:

  Kedde, M., et al. Cell Cycle 7 (7) :899-903 (2008)

• Background Reference 04:

  Linger, R., et al. Genes Chromosomes Cancer 47 (3) :247-252 (2008)

• Other Product Names:

  Dead end protein homolog 1, RNA-binding motif, single-stranded-interacting protein 4, DND1, RBMS4

• Tested Applications:

  WB

• Protein ID:

  60389799

• Physical Properties:

  Liquid