DND1 Antibody

• Background :

  This gene encodes a protein that binds to microRNA-targeting sequences of mRNAs, inhibiting microRNA-mediated repression. Reduced expression of this gene has been implicated in tongue squamous cell carcinoma. Two pseudogenes of this gene are located on the long arm of chromosome 17.

• NCBI Gene ID :

  373863

• Swiss Prot :

  Q8IYX4

• Accession Number :

  Q8IYX4

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This DND1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 198-226 amino acids from the Central region of human DND1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  39 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  DND1

• NCBI Official Name :

  Dead end protein homolog 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Liu, X., et al. FEBS Lett. 584 (18) :4115-4120 (2010)

• Background Reference 02 :

  Sijmons, R.H., et al. Fam. Cancer 9 (3) :439-442 (2010)

• Background Reference 03 :

  Kedde, M., et al. Cell Cycle 7 (7) :899-903 (2008)

• Background Reference 04 :

  Linger, R., et al. Genes Chromosomes Cancer 47 (3) :247-252 (2008)

• Other Product Names :

  Dead end protein homolog 1, RNA-binding motif, single-stranded-interacting protein 4, DND1, RBMS4

• Tested Applications :

  WB

• Protein ID :

  60389799

• Physical Properties :

  Liquid