VPS11 Antibody

CAT: 0223-58-530Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-530Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps11 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
NCBI Gene ID
55823
Swiss Prot
Q9H270
Accession Number
Q9H270
Host
Rabbit
Reactivity
Human
Immunogen
This VPS11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 772-800 amino acids from the C-terminal region of human VPS11.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
108 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
VPS11
NCBI Official Name
Vacuolar protein sorting-associated protein 11 homolog
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care (2010) In press :
Background Reference 02
Talmud, P.J., et al. Am. J. Hum. Genet. 85 (5) :628-642 (2009)
Background Reference 03
Zhu, G.D., et al. Mol. Biol. Cell 20 (4) :1223-1240 (2009)
Background Reference 04
Wan, D., et al. Proc. Natl. Acad. Sci. U.S.A. 101 (44) :15724-15729 (2004)
Other Product Names
Vacuolar protein sorting-associated protein 11 homolog, hVPS11, RING finger protein 108, VPS11, RNF108
Tested Applications
WB
Protein ID
23396928
Physical Properties
Liquid

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