CXXC1 Antibody

• Background:

  Proteins that contain a CXXC motif within their DNA-binding domain, such as CXXC1, recognize CpG sequences and regulate gene expression (Carlone and Skalnik, 2001 [PubMed 11604496]) .

• NCBI Gene ID:

  30827

• Swiss Prot:

  Q9P0U4

• Accession Number:

  Q9P0U4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CXXC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 326-354 amino acids from the Central region of human CXXC1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  76 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CXXC1

• NCBI Official Name:

  CXXC-type zinc finger protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Crowther-Swanepoel, D., et al. Nat. Genet. 42 (2) :132-136 (2010)

• Background Reference 02:

  Tate, C.M., et al. Mol. Cell. Biol. 29 (14) :3817-3831 (2009)

• Background Reference 03:

  Butler, J.S., et al. DNA Cell Biol. 27 (10) :533-543 (2008)

• Background Reference 04:

  Ansari, K.I., et al. Biochim. Biophys. Acta 1779 (1) :66-73 (2008)

• Other Product Names:

  CXXC-type zinc finger protein 1, CpG-binding protein, PHD finger and CXXC domain-containing protein 1, CXXC1, CFP1, CGBP, PCCX1, PHF18

• Tested Applications:

  WB

• Protein ID:

  20138037

• Physical Properties:

  Liquid