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SSR4 Antibody

CAT: 0223-58-470Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-470Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
SSR4, also called TRAPD, is assumed to be involved in protein secretion. It is located in the Xq28 region, arranged in a compact head-to-head manner with the IDH3G gene. These two genes are driven by a bidirectional promoter located between them, and encode proteins involved in unrelated biochemical pathways located in different compartments of the cell. The nontranscribed intergenic region represents only 133 bp and is embedded in a CpG island. The CpG island functions as a bidirectional promoter to initiate the transcription of both functionally unrelated genes with distinct expression patterns. SSR4 consists of six exons and is approximately 70 kb telomeric to the ALD gene. Although alternative splicing of exon 5 has not been detected in human SSR4, transcript variants missing the region homologous to human exon 5 have been detected in both Xenopus laevis and Mus musculus.
NCBI Gene ID
6748
Swiss Prot
P51571
Accession Number
P51571
Host
Rabbit
Reactivity
Human
Immunogen
This SSR4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the Central region of human SSR4.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
19 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SSR4
NCBI Official Name
Translocon-associated protein subunit delta
NCBI Organism
Homo sapiens
Background Reference 01
Ewing, R.M., et al. Mol. Syst. Biol. 3, 89 (2007) :
Background Reference 02
Wang, Z., et al. Melanoma Res. 14 (2) :107-114 (2004)
Background Reference 03
Miyazaki, K., et al. J. Biol. Chem. 279 (12) :11327-11335 (2004)
Background Reference 04
Wang, L., et al. FEBS Lett. 457 (3) :316-322 (1999)
Other Product Names
Translocon-associated protein subunit delta, TRAP-delta, Signal sequence receptor subunit delta, SSR-delta, SSR4, TRAPD
Tested Applications
WB
Protein ID
1711550
Physical Properties
Liquid

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