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NFS1 Antibody

CAT: 0223-58-465Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-465Size:400 µL
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Background
Iron-sulfur clusters are required for the function of many cellular enzymes. The proteins encoded by this gene supply inorganic sulfur to these clusters by removing the sulfur from cysteine, creating alanine in the process. This gene uses alternate in-frame translation initiation sites to generate mitochondrial forms and cytoplasmic/nuclear forms. Selection of the alternative initiation sites is determined by the cytosolic pH. The encoded proteins belong to the class-V family of pyridoxal phosphate-dependent aminotransferases. Alternatively spliced transcript variants have been described.
NCBI Gene ID
9054
Swiss Prot
Q9Y697
Accession Number
Q9Y697
Host
Rabbit
Reactivity
Human
Immunogen
This NFS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 121-149 amino acids from the Central region of human NFS1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
50 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
NFS1
NCBI Official Name
Cysteine desulfurase, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Naamati, A., et al. J. Biol. Chem. 284 (44) :30200-30208 (2009)
Background Reference 02
Marelja, Z., et al. J. Biol. Chem. 283 (37) :25178-25185 (2008)
Background Reference 03
Wu, C., et al. Proteomics 7 (11) :1775-1785 (2007)
Background Reference 04
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Other Product Names
Cysteine desulfurase, mitochondrial, NFS1, NIFS
Tested Applications
WB
Protein ID
62512153
Physical Properties
Liquid

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