Products for Research Use Only
RegisterLogin

SIAH1 Antibody

CAT: 0223-58-452Size: 400 µLDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0223-58-452Size:400 µL
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
SIAH1 is a protein that is a member of the seven in absentia homolog (SIAH) family. The protein is an E3 ligase and is involved in ubiquitination and proteasome-mediated degradation of specific proteins. The activity of this ubiquitin ligase has been implicated in the development of certain forms of Parkinson's disease, the regulation of the cellular response to hypoxia and induction of apoptosis. Alternative splicing results in several additional transcript variants, some encoding different isoforms and others that have not been fully characterized. [provided by RefSeq].
NCBI Gene ID
6477
Swiss Prot
Q8IUQ4
Accession Number
Q8IUQ4
Host
Rabbit
Reactivity
Human
Immunogen
This SIAH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 92-120 amino acids from the Central region of human SIAH1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
31 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SIAH1
NCBI Official Name
E3 ubiquitin-protein ligase SIAH1
NCBI Organism
Homo sapiens
Background Reference 01
Wu, H., et al. Biochem. Biophys. Res. Commun. 397 (3) :391-396 (2010)
Background Reference 02
Wen, Y.Y., et al. Mol. Carcinog. 49 (5) :440-449 (2010)
Background Reference 03
Dimitrova, Y.N., et al. J. Biol. Chem. 285 (18) :13507-13516 (2010)
Background Reference 04
Bruzzoni-Giovanelli, H., et al. J. Exp. Clin. Cancer Res. 29, 10 (2010) :
Other Product Names
E3 ubiquitin-protein ligase SIAH1, 632-, Seven in absentia homolog 1, Siah-1, Siah-1a, SIAH1, HUMSIAH
Tested Applications
WB
Protein ID
46577493
Physical Properties
Liquid

Related Products

CatalogName
45-144PSIAH1 Peptide
55-506SIAH3 Antibody
62-085SIAH2 Antibody
64-160WAS Antibody
60-596WAS Antibody
13-349WAS Antibody
62-828Neprilysin Antibody
61-580CAPZB Antibody
55-580HCG_2024410 Antibody
30-580ACPT Antibody

Alternative Products

CatalogName
CSB-PA021287GA01HUSIAH1 Antibody

Popular Products