TP53BP2 Antibody

• Background :

  TP53BP2 is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. It is localized to the perinuclear region of the cytoplasm, and regulates apoptosis and cell growth through interactions with other regulatory molecules including members of the p53 family. Multiple transcript variants encoding different isoforms have been found for this gene.

• NCBI Gene ID :

  7159

• Swiss Prot :

  Q13625

• Accession Number :

  Q13625

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This TP53BP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 93-122 amino acids from the N-terminal region of human TP53BP2.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  126 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  TP53BP2

• NCBI Official Name :

  Apoptosis-stimulating of p53 protein 2

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Rose, J. Phd, et al. Mol. Med. (2010) In press :

• Background Reference 02 :

  Zhao, J., et al. Hepatology 51 (1) :142-153 (2010)

• Background Reference 03 :

  Hirata, H., et al. J. Urol. 182 (2) :721-727 (2009)

• Background Reference 04 :

  Kweekel, D.M., et al. Br. J. Cancer 101 (2) :357-362 (2009)

• Other Product Names :

  Apoptosis-stimulating of p53 protein 2, Bcl2-binding protein, Bbp, Renal carcinoma antigen NY-REN-51, Tumor suppressor p53-binding protein 2, 53BP2, p53-binding protein 2, p53BP2, TP53BP2, ASPP2, BBP

• Tested Applications :

  WB

• Protein ID :

  33860140

• Physical Properties :

  Liquid