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PPIF Antibody

CAT: 0223-58-411Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-411Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PPIF is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein is part of the mitochondrial permeability transition pore in the inner mitochondrial membrane. Activation of this pore is thought to be involved in the induction of apoptotic and necrotic cell death.
NCBI Gene ID
10105
Swiss Prot
P30405
Accession Number
P30405
Host
Rabbit
Reactivity
Human
Immunogen
This PPIF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 103-131 amino acids from the Central region of human PPIF.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle, Immunology, Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
22 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PPIF
NCBI Official Name
Peptidyl-prolyl cis-trans isomerase F, mitochondrial
NCBI Organism
Homo sapiens
Background Reference 01
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 02
He, Y., et al. Invest. Ophthalmol. Vis. Sci. 49 (11) :4912-4922 (2008)
Background Reference 03
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 04
Lin, D.T., et al. J. Biol. Chem. 277 (34) :31134-31141 (2002)
Other Product Names
Peptidyl-prolyl cis-trans isomerase F, mitochondrial, PPIase F, Cyclophilin D, CyP-D, CypD, Cyclophilin F, Mitochondrial cyclophilin, CyP-M, Rotamase F, PPIF, CYP3
Tested Applications
WB
Protein ID
231968
Physical Properties
Liquid

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