PPIE Antibody

• Background :

  PPIE is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activityThe protein encoded by this gene is a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. This protein contains a highly conserved cyclophilin (CYP) domain as well as an RNA-binding domain. It was shown to possess PPIase and protein folding activities and also exhibit RNA-binding activity. Three alternatively spliced transcript variants encoding distinct isoforms have been observed.

• NCBI Gene ID :

  10450

• Swiss Prot :

  Q9UNP9

• Accession Number :

  NP_982282

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat, Dog, Zebrafish, Drosophila

• Immunogen :

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human PPIE.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  Antibody is purified by protein A chromatography method.

• Positive Control :

  Cat. No. 1205 - Jurkat Cell Lysate

• Concentration :

  Batch dependent

• Buffer :

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store PPIE antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight :

  26 kDa, 33 kDa, 33 kDa

• Applications Notes :

  PPIE antibody can be used for detection of PPIE by ELISA at 1:312500. PPIE antibody can be used for detection of PPIE by western blot at 2.5 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol :

  PPIE

• NCBI Official Name :

  Peptidylprolyl isomerase E (cyclophilin E)

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Fair, K., (2001) Mol. Cell. Biol. 21 (10), 3589-3597.

• Other Product Names :

  PPIE, CYP33, CYP-33

• Tested Applications :

  ELISA, WB

• Protein ID :

  45439318

• Physical Properties :

  Liquid