VSX1 Antibody

• Background:

  VSX1 contains a paired-like homeodomain and binds to the core of the locus control region of the red/green visual pigment gene cluster. The encoded protein may regulate expression of the cone opsin genes early in development. Mutations in this gene can cause posterior polymorphous corneal dystrophy and keratoconus.

• NCBI Gene ID:

  30813

• Swiss Prot:

  Q9NZR4

• Accession Number:

  Q9NZR4

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This VSX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 125-154 amino acids from the Central region of human VSX1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  VSX1

• NCBI Official Name:

  Visual system homeobox 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Dash, D.P., et al. Eye (Lond) 24 (6) :1085-1092 (2010)

• Background Reference 03:

  Stabuc-Silih, M., et al. Cornea 29 (2) :172-176 (2010)

• Background Reference 04:

  Stabuc-Silih, M., et al. Acta Dermatovenerol Alp Panonica Adriat 19 (2) :3-10 (2010)

• Other Product Names:

  Visual system homeobox 1, Homeodomain protein RINX, Retinal inner nuclear layer homeobox protein, Transcription factor VSX1, VSX1, RINX

• Tested Applications:

  WB

• Protein ID:

  25009572

• Physical Properties:

  Liquid