CC2D1A Antibody

CAT: 0223-58-358Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-358Size:400 µL
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Background
CC2D1A is a transcriptional repressor that binds to a conserved 14-bp 5'-repressor element and regulates expression of the 5-hydroxytryptamine (serotonin) receptor 1A gene in neuronal cells. The DNA binding and transcriptional repressor activities of the protein are inhibited by calcium. A mutation in this gene results in nonsyndromic mental retardation-3.
NCBI Gene ID
54862
Swiss Prot
Q6P1N0
Accession Number
Q6P1N0
Host
Rabbit
Reactivity
Human
Immunogen
This CC2D1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 143-172 amino acids from the N-terminal region of human CC2D1A.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
104 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CC2D1A
NCBI Official Name
Coiled-coil and C2 domain-containing protein 1A
NCBI Organism
Homo sapiens
Background Reference 01
Zhao, M., et al. J. Biol. Chem. 285 (32) :24372-24380 (2010)
Background Reference 02
Nakamura, A., et al. Biochem. Biophys. Res. Commun. 393 (4) :872-876 (2010)
Background Reference 03
Nakamura, A., et al. J. Cell Biol. 187 (5) :607-614 (2009)
Background Reference 04
McKay, G.J., et al. Invest. Ophthalmol. Vis. Sci. 50 (2) :533-539 (2009)
Other Product Names
Coiled-coil and C2 domain-containing protein 1A, Akt kinase-interacting protein 1, Five prime repressor element under dual repression-binding protein 1, FRE under dual repression-binding protein 1, Freud-1, Putative NF-kappa-B-activating protein 023N, CC2D1A, AKI1
Tested Applications
WB
Protein ID
74737148
Physical Properties
Liquid

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