DNAH2 Antibody

• Background:

  Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]) .

• NCBI Gene ID:

  146754

• Swiss Prot:

  Q9P225

• Accession Number:

  Q9P225

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This DNAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the N-terminal region of human DNAH2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  508 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  DNAH2

• NCBI Official Name:

  Dynein heavy chain 2, axonemal

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Barrett, J.C., et al. Nat. Genet. (2009) In press :

• Background Reference 02:

  Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :

• Background Reference 03:

  Chapelin, C., et al. FEBS Lett. 412 (2) :325-330 (1997)

• Other Product Names:

  Dynein heavy chain 2, axonemal, Axonemal beta dynein heavy chain 2, Ciliary dynein heavy chain 2, Dynein heavy chain domain-containing protein 3, DNAH2, DNAHC2, DNHD3, KIAA1503

• Tested Applications:

  WB

• Protein ID:

  172044680

• Physical Properties:

  Liquid