GABPB1 Antibody

• Background:

  This gene encodes the GA-binding protein transcription factor, beta subunit. This protein forms a tetrameric complex with the alpha subunit, and stimulates transcription of target genes. The encoded protein may be involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. The crystal structure of a similar protein in mouse has been resolved as a ternary protein complex. Multiple transcript variants encoding distinct isoforms have been identified for this gene.

• NCBI Gene ID:

  2553

• Swiss Prot:

  Q06547

• Accession Number:

  Q06547

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This GABPB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 337-365 amino acids from the C-terminal region of human GABPB1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  42 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  GABPB1

• NCBI Official Name:

  GA-binding protein subunit beta-1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Eynon, N., et al. Physiol. Genomics 41 (1) :78-81 (2010)

• Background Reference 02:

  Venkatesan, K., et al. Nat. Methods 6 (1) :83-90 (2009)

• Background Reference 03:

  Lu, Y., et al. J. Lipid Res. 49 (12) :2582-2589 (2008)

• Background Reference 04:

  Vercauteren, K., et al. J. Biol. Chem. 283 (18) :12102-12111 (2008)

• Other Product Names:

  GA-binding protein subunit beta-1, GABP subunit beta-1, GABPB-1, GABP subunit beta-2, GABPB-2, Nuclear respiratory factor 2, Transcription factor E4TF1-47, Transcription factor E4TF1-53, GABPB1, E4TF1B, GABPB, GABPB2

• Tested Applications:

  WB

• Protein ID:

  23503070

• Physical Properties:

  Liquid