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HCRTR1 Antibody

CAT: 0223-58-271Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-271Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a G-protein coupled receptor involved in the regulation of feeding behavior. The encoded protein selectively binds the hypothalamic neuropeptide orexin A. A related gene (HCRTR2) encodes a G-protein coupled receptor that binds orexin A and orexin B.
NCBI Gene ID
3061
Swiss Prot
O43613
Accession Number
O43613
Host
Rabbit
Reactivity
Human
Immunogen
This HCRTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 270-298 amino acids from the Central region of human HCRTR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
48 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HCRTR1
NCBI Official Name
Orexin receptor type 1
NCBI Organism
Homo sapiens
Background Reference 01
Peltonen, H.M., et al. Biochim. Biophys. Acta 1803 (10) :1206-1212 (2010)
Background Reference 02
Saus, E., et al.Psychiatr Res 44 (14) :971-978 (2010)
Background Reference 03
Pinheiro, A.P., et al. Am. J. Med. Genet.Neuropsychiatr. Genet. 153B (5), 1070-1080 (2010) :
Background Reference 04
Turunen, P.M., et al. Br. J. Pharmacol. 159 (1) :212-221 (2010)
Other Product Names
Orexin receptor type 1, Ox-1-R, Ox1-R, Ox1R, Hypocretin receptor type 1, HCRTR1
Tested Applications
WB
Physical Properties
Liquid

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