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VPS45 Antibody

CAT: 0223-58-263Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-263Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec1 domain family, and shows a high degree of sequence similarity to mouse, rat and yeast Vps45. The exact function of this gene is not known, but its high expression in peripheral blood mononuclear cells suggests a role in trafficking proteins, including inflammatory mediators. [provided by RefSeq].
NCBI Gene ID
11311
Swiss Prot
Q9NRW7
Accession Number
Q9NRW7
Host
Rabbit
Reactivity
Human
Immunogen
This VPS45 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 461-489 amino acids from the C-terminal region of human VPS45.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
65 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
VPS45
NCBI Official Name
Vacuolar protein sorting-associated protein 45
NCBI Organism
Homo sapiens
Background Reference 01
Rahajeng, J., et al. Exp. Cell Res. 316 (5) :859-874 (2010)
Background Reference 02
Kim, B.Y., et al. Biochem. Biophys. Res. Commun. 311 (3) :577-582 (2003)
Background Reference 03
Dulubova, I., et al. EMBO J. 21 (14) :3620-3631 (2002)
Background Reference 04
De Renzis, S., et al. Nat. Cell Biol. 4 (2) :124-133 (2002)
Other Product Names
Vacuolar protein sorting-associated protein 45, h-VPS45, hlVps45, VPS45, VPS45A, VPS45B
Tested Applications
WB
Protein ID
23396937
Physical Properties
Liquid

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