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MRC2 Antibody

CAT: 0223-58-238Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-238Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
MRC2 is a recycling endocytic receptor that functions in cell motility and remodeling of the extracellular matrix by promoting cell migration and uptake of collagens for intracellular degradation (Wienke et al., 2007 [PubMed 17974964]) .[supplied by OMIM].
NCBI Gene ID
9902
Swiss Prot
Q9UBG0
Accession Number
Q9UBG0
Host
Rabbit
Reactivity
Human
Immunogen
This MRC2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 798-827 amino acids from the Central region of human MRC2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
167 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
MRC2
NCBI Official Name
C-type mannose receptor 2
NCBI Organism
Homo sapiens
Background Reference 01
Messaritou, G., et al. J. Cell. Sci. 122 (PT 22), 4042-4048 (2009) :
Background Reference 02
Wu, X., et al. Cancer Prev Res (Phila Pa) 2 (7) :617-624 (2009)
Background Reference 03
Wienke, D., et al. Cancer Res. 67 (21) :10230-10240 (2007)
Background Reference 04
Sulek, J., et al. J. Histochem. Cytochem. 55 (4) :347-353 (2007)
Other Product Names
C-type mannose receptor 2, C-type lectin domain family 13 member E, Endocytic receptor 180, Macrophage mannose receptor 2, Urokinase-type plasminogen activator receptor-associated protein, UPAR-associated protein, Urokinase receptor-associated protein, CD280, MRC2, CLEC13E, ENDO180, KIAA0709, UPARAP
Tested Applications
WB
Protein ID
317373394
Physical Properties
Liquid

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