CAPG Antibody

• Background :

  This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. [provided by RefSeq].

• NCBI Gene ID :

  822

• Swiss Prot :

  P40121

• Accession Number :

  P40121

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human CAPG.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  38 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  CAPG

• NCBI Official Name :

  Macrophage-capping protein

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Li, M.X., et al. Med. Oncol. 27 (1) :134-144 (2010)

• Background Reference 02 :

  Burillo, E., et al. Atherosclerosis 207 (1) :32-37 (2009)

• Background Reference 03 :

  Zhang, R., et al. Am. J. Respir. Cell Mol. Biol. 41 (4) :467-475 (2009)

• Background Reference 04 :

  Hubert, T., et al. Biochem. Biophys. Res. Commun. 380 (1) :166-170 (2009)

• Other Product Names :

  Macrophage-capping protein, Actin regulatory protein CAP-G, CAPG, AFCP, MCP

• Tested Applications :

  WB

• Protein ID :

  313104088

• Physical Properties :

  Liquid