CAPG Antibody

• Background:

  This gene encodes a member of the gelsolin/villin family of actin-regulatory proteins. The encoded protein reversibly blocks the barbed ends of F-actin filaments in a Ca2+ and phosphoinositide-regulated manner, but does not sever preformed actin filaments. By capping the barbed ends of actin filaments, the encoded protein contributes to the control of actin-based motility in non-muscle cells. Alternatively spliced transcript variants have been observed, but have not been fully described. [provided by RefSeq].

• NCBI Gene ID:

  822

• Swiss Prot:

  P40121

• Accession Number:

  P40121

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This CAPG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 181-209 amino acids from the Central region of human CAPG.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  CAPG

• NCBI Official Name:

  Macrophage-capping protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Li, M.X., et al. Med. Oncol. 27 (1) :134-144 (2010)

• Background Reference 02:

  Burillo, E., et al. Atherosclerosis 207 (1) :32-37 (2009)

• Background Reference 03:

  Zhang, R., et al. Am. J. Respir. Cell Mol. Biol. 41 (4) :467-475 (2009)

• Background Reference 04:

  Hubert, T., et al. Biochem. Biophys. Res. Commun. 380 (1) :166-170 (2009)

• Other Product Names:

  Macrophage-capping protein, Actin regulatory protein CAP-G, CAPG, AFCP, MCP

• Tested Applications:

  WB

• Protein ID:

  313104088

• Physical Properties:

  Liquid