STMN2 Antibody

• Background:

  This gene encodes a member of the stathmin family of phosphoproteins. Stathmin proteins function in microtubule dynamics and signal transduction. The encoded protein plays a regulatory role in neuronal growth and is also thought to be involved in osteogenesis. Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease. Alternatively spliced transcript variants have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 6.

• NCBI Gene ID:

  11075

• Swiss Prot:

  Q93045

• Accession Number:

  Q93045

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This STMN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 145-173 amino acids from the C-terminal region of human STMN2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Chicken, Mouse, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  21 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  STMN2

• NCBI Official Name:

  Stathmin-2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Paradis, V., et al. Am. J. Pathol. 177 (4) :1791-1797 (2010)

• Background Reference 02:

  Rowe, D.D., et al. Brain Res. (2010) In press :

• Background Reference 03:

  Alves, M.M., et al. Hum. Mol. Genet. 19 (18) :3642-3651 (2010)

• Background Reference 04:

  Xu, H., et al. J. Biol. Chem. 285 (6) :3548-3553 (2010)

• Other Product Names:

  Stathmin-2, Superior cervical ganglion-10 protein, Protein SCG10, STMN2, SCG10, SCGN10

• Tested Applications:

  WB

• Protein ID:

  51704330

• Physical Properties:

  Liquid