CTBP1 Antibody

• Background:

  This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.

• NCBI Gene ID:

  1487

• Swiss Prot:

  Q13363

• Accession Number:

  Q13363

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  This CTBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 413-440 amino acids from the C-terminal region of human CTBP1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  48 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  CTBP1

• NCBI Official Name:

  C-terminal-binding protein 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Roukens, M.G., et al. Nat. Cell Biol. 12 (10) :933-942 (2010)

• Background Reference 02:

  Choi, H.J., et al. Biochem. Biophys. Res. Commun. 400 (3) :396-402 (2010)

• Background Reference 03:

  Merrill, J.C., et al. J. Mol. Biol. 398 (5) :657-671 (2010)

• Background Reference 04:

  Davila, S., et al. Genes Immun. 11 (3) :232-238 (2010)

• Other Product Names:

  C-terminal-binding protein 1, CtBP1, 111-, CTBP1, CTBP

• Tested Applications:

  WB, IF

• Protein ID:

  6014741

• Physical Properties:

  Liquid