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SH2B1 Antibody

CAT: 0223-58-193Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-193Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a member of the SH2-domain containing mediators family. The encoded protein mediates activation of various kinases and may function in cytokine and growth factor receptor signaling and cellular transformation. Alternatively spliced transcript variants have been described. [provided by RefSeq].
NCBI Gene ID
25970
Swiss Prot
Q9NRF2
Accession Number
Q9NRF2
Host
Rabbit
Reactivity
Human
Immunogen
This SH2B1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 725-752 amino acids from the C-terminal region of human SH2B1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
79 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
SH2B1
NCBI Official Name
SH2B adapter protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Fontaine-Bisson, B., et al. Diabetologia 53 (10) :2155-2162 (2010)
Background Reference 02
Holzapfel, C., et al. IntObes (Lond) 34 (10) :1538-1545 (2010)
Background Reference 03
Shi, J., et al. Am. J. Epidemiol. 172 (3) :244-254 (2010)
Background Reference 04
Haupt, A., et al. Obesity (Silver Spring) 18 (6) :1212-1217 (2010)
Other Product Names
SH2B adapter protein 1, Pro-rich, PH and SH2 domain-containing signaling mediator, PSM, SH2 domain-containing protein 1B, SH2B1, KIAA1299, SH2B
Tested Applications
WB
Protein ID
313104186
Physical Properties
Liquid

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MBS8516837-01SH2B1 Antibody

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