PFN2 Antibody

CAT: 0223-58-192Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-192Size:400 µL
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Background
The protein encoded by this gene is a ubiquitous actin monomer-binding protein belonging to the profilin family. It is thought to regulate actin polymerization in response to extracellular signals. There are two alternatively spliced transcript variants encoding different isoforms described for this gene.
NCBI Gene ID
5217
Swiss Prot
P35080
Accession Number
P35080
Host
Rabbit
Reactivity
Human
Immunogen
This PFN2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 110-139 amino acids from the C-terminal region of human PFN2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Monkey, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
15 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PFN2
NCBI Official Name
Profilin-2
NCBI Organism
Homo sapiens
Background Reference 01
Shao, J., et al. Mol. Cell. Biol. 28 (17) :5196-5208 (2008)
Background Reference 02
Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)
Background Reference 03
Xu, J., et al. Cell. Signal. 19 (7) :1575-1582 (2007)
Background Reference 04
Stelzl, U., et al. Cell 122 (6) :957-968 (2005)
Other Product Names
Profilin-2, Profilin II, PFN2
Tested Applications
WB
Protein ID
20178322
Physical Properties
Liquid

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