NCS1 Antibody

• Background:

  NCS1 is a member of the neuronal calcium sensor gene family, which encode calcium-binding proteins expressed predominantly in neurons. NCS1 regulates G protein-coupled receptor phosphorylation in a calcium-dependent manner and can substitute for calmodulin. This protein is thought to be associated with secretory granules and may be involved in the regulation of neurosecretion.

• NCBI Gene ID:

  23413

• Swiss Prot:

  P62166

• Accession Number:

  P62166

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This NCS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-144 amino acids from the Central region of human NCS1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Chicken, Mouse, Rat, Xenopus

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  22 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  NCS1

• NCBI Official Name:

  Neuronal calcium sensor 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Koh, P.O., et al., Proc. Natl. Acad. Sci. U.S.A. 100 (1) :313-317 (2003) .

• Background Reference 02:

  Bourne, Y., et al., J. Biol. Chem. 276 (15) :11949-11955 (2001) .

• Background Reference 03:

  Burgoyne, R.D., et al., Biochem. J. 353 (Pt 1), 1-12 (2001) .

• Other Product Names:

  Neuronal calcium sensor 1, NCS-1, Frequenin homolog, Frequenin-like protein, Frequenin-like ubiquitous protein, NCS1, FLUP, FREQ

• Tested Applications:

  WB, IHC-P, Flow

• Protein ID:

  49065666

• Physical Properties:

  Liquid