AMFR Antibody

CAT: 0223-58-127Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-127Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.
NCBI Gene ID
267
Swiss Prot
Q9UKV5
Accession Number
Q9UKV5
Host
Rabbit
Reactivity
Human
Immunogen
This AMFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-400 amino acids from the Central region of human AMFR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
73 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
AMFR
NCBI Official Name
E3 ubiquitin-protein ligase AMFR
NCBI Organism
Homo sapiens
Background Reference 01
Joshi, B., et al. J. Biol. Chem. 285 (12) :8830-8839 (2010)
Background Reference 02
Bernardi, K.M., et al. Mol. Biol. Cell 21 (1) :140-151 (2010)
Background Reference 03
Ballar, P., et al. Int. J. Biochem. Cell Biol. 42 (1) :167-173 (2010)
Background Reference 04
Shmueli, A., et al. Biochem. Biophys. Res. Commun. 390 (3) :758-762 (2009)
Other Product Names
E3 ubiquitin-protein ligase AMFR, 632-, Autocrine motility factor receptor, AMF receptor, RING finger protein 45, gp78, AMFR, RNF45
Tested Applications
WB
Protein ID
34922250
Physical Properties
Liquid

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