AMFR Antibody

• Background :

  Autocrine motility factor is a tumor motility-stimulating protein secreted by tumor cells. The protein encoded by this gene is a glycosylated transmembrane protein and a receptor for autocrine motility factor. The receptor, which shows some sequence similarity to tumor protein p53, is localized to the leading and trailing edges of carcinoma cells.

• NCBI Gene ID :

  267

• Swiss Prot :

  Q9UKV5

• Accession Number :

  Q9UKV5

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This AMFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371-400 amino acids from the Central region of human AMFR.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Cell Cycle

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  73 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  AMFR

• NCBI Official Name :

  E3 ubiquitin-protein ligase AMFR

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Joshi, B., et al. J. Biol. Chem. 285 (12) :8830-8839 (2010)

• Background Reference 02 :

  Bernardi, K.M., et al. Mol. Biol. Cell 21 (1) :140-151 (2010)

• Background Reference 03 :

  Ballar, P., et al. Int. J. Biochem. Cell Biol. 42 (1) :167-173 (2010)

• Background Reference 04 :

  Shmueli, A., et al. Biochem. Biophys. Res. Commun. 390 (3) :758-762 (2009)

• Other Product Names :

  E3 ubiquitin-protein ligase AMFR, 632-, Autocrine motility factor receptor, AMF receptor, RING finger protein 45, gp78, AMFR, RNF45

• Tested Applications :

  WB

• Protein ID :

  34922250

• Physical Properties :

  Liquid