Mouse Erbb2 Antibody

• Background:

  Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity) .

• NCBI Gene ID:

  13866

• Swiss Prot:

  P70424

• Accession Number:

  P70424

• Host:

  Rabbit

• Reactivity:

  Mouse

• Immunogen:

  This Mouse Erbb2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the Central region of mouse Erbb2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  139 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  Erbb2

• NCBI Official Name:

  Receptor tyrosine-protein kinase erbB-2

• NCBI Organism:

  Mus musculus

• Background Reference 01:

  Cabodi, S., et al. FASEB J. 24 (10) :3796-3808 (2010)

• Background Reference 02:

  Johnson, E., et al. J. Biol. Chem. 285 (38) :29491-29501 (2010)

• Background Reference 03:

  Huck, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (35) :15559-15564 (2010)

• Background Reference 04:

  Chuang, T.D., et al. J. Biol. Chem. 285 (31) :23598-23606 (2010)

• Other Product Names:

  Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, CD340, Erbb2, Kiaa3023, Neu

• Tested Applications:

  WB

• Physical Properties:

  Liquid