Mouse Erbb2 Antibody

CAT: 0223-58-126Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-126Size:400 µL
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. Binds to the 5'-TCAAATTC-3' sequence in the MT-CO2 promoter and activates its transcription (By similarity) .
NCBI Gene ID
13866
Swiss Prot
P70424
Accession Number
P70424
Host
Rabbit
Reactivity
Mouse
Immunogen
This Mouse Erbb2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 531-559 amino acids from the Central region of mouse Erbb2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
139 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
Erbb2
NCBI Official Name
Receptor tyrosine-protein kinase erbB-2
NCBI Organism
Mus musculus
Background Reference 01
Cabodi, S., et al. FASEB J. 24 (10) :3796-3808 (2010)
Background Reference 02
Johnson, E., et al. J. Biol. Chem. 285 (38) :29491-29501 (2010)
Background Reference 03
Huck, L., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (35) :15559-15564 (2010)
Background Reference 04
Chuang, T.D., et al. J. Biol. Chem. 285 (31) :23598-23606 (2010)
Other Product Names
Receptor tyrosine-protein kinase erbB-2, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, p185erbB2, CD340, Erbb2, Kiaa3023, Neu
Tested Applications
WB
Physical Properties
Liquid

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