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TADA2L Antibody

CAT: 0223-58-092Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-092Size:400 µL
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Background
Many DNA-binding transcriptional activator proteins enhance the initiation rate of RNA polymerase II-mediated gene transcription by interacting functionally with the general transcription machinery bound at the basal promoter. Adaptor proteins are usually required for this activation, possibly to acetylate and destabilize nucleosomes, thereby relieving chromatin constraints at the promoter. The protein encoded by this gene is a transcriptional activator adaptor and has been found to be part of the PCAF histone acetylase complex. Several alternatively spliced transcript variants encoding different isoforms of this gene have been described, but the full-length nature of some of these variants has not been determined.
NCBI Gene ID
6871
Swiss Prot
O75478
Accession Number
O75478
Host
Rabbit
Reactivity
Human
Immunogen
This TADA2L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 202-230 amino acids from the Central region of human TADA2L.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
52 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
TADA2A
NCBI Official Name
Transcriptional adapter 2-alpha
NCBI Organism
Homo sapiens
Background Reference 01
Ruano, G., et al. Pharmacogenomics 11 (7) :959-971 (2010)
Background Reference 02
Yang, M., et al. Cancer Biol. Ther. 7 (1) :120-128 (2008)
Background Reference 03
Lamesch, P., et al. Genomics 89 (3) :307-315 (2007)
Background Reference 04
Qian, C., et al. Nat. Struct. Mol. Biol. 12 (12) :1078-1085 (2005)
Other Product Names
Transcriptional adapter 2-alpha, Transcriptional adapter 2-like, ADA2-like protein, TADA2A, TADA2L
Tested Applications
WB
Physical Properties
Liquid

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