SDR16C5 Antibody

• Background:

  RDHE2 belongs to a family of short-chain alcohol dehydrogenases/reductases that catalyze the first and rate-limiting step that generates retinaldehyde from retinol (Matsuzaka et al., 2002 [PubMed 12372410]) .

• NCBI Gene ID:

  195814

• Swiss Prot:

  Q8N3Y7

• Accession Number:

  Q8N3Y7

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This SDR16C5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 123-151 amino acids from the Central region of human SDR16C5.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Obesity, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  34 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  SDR16C5

• NCBI Official Name:

  Epidermal retinol dehydrogenase 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :

• Background Reference 02:

  Zhao, J., et al. BMC Med. Genet. 11, 96 (2010) :

• Background Reference 03:

  Takahashi, Y., et al. Biochem. J. 419 (1) :113-122 (2009)

• Background Reference 04:

  Soranzo, N., et al. PLoS Genet. (4), E1000445 (2009) :

• Other Product Names:

  Epidermal retinol dehydrogenase 2, EPHD-2, RDH-E2, Retinal short-chain dehydrogenase reductase 2, retSDR2, Short-chain dehydrogenase/reductase family 16C member 5, SDR16C5, RDHE2

• Tested Applications:

  WB

• Protein ID:

  74750974

• Physical Properties:

  Liquid