CACNB2 Antibody

CAT: 0223-58-054Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-58-054Size:400 µL
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Background
This gene encodes a subunit of a voltage-dependent calcium channel protein which is a member of the voltage-gated calcium channel superfamily. The gene product was originally identified as an antigen target in Lambert-Eaton myasthenic syndrome which is an autoimmune disorder. Mutations in this gene are associated with Brugada symdrome. Alternatively spliced variants have been identified for this gene.
NCBI Gene ID
783
Swiss Prot
Q08289
Accession Number
Q08289
Host
Rabbit
Reactivity
Human
Immunogen
This CACNB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-261 amino acids from the Central region of human CACNB2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CACNB2
NCBI Official Name
Voltage-dependent L-type calcium channel subunit beta-2
NCBI Organism
Homo sapiens
Background Reference 01
Burashnikov, E., et al. Heart Rhythm (2010) In press :
Background Reference 02
Shimada, M., et al. Hum. Genet. 128 (4) :433-441 (2010)
Background Reference 03
Takeuchi, F., et al. Circulation 121 (21) :2302-2309 (2010)
Background Reference 04
Hong, K.W., et al. J. Hum. Genet. 55 (6) :336-341 (2010)
Other Product Names
Voltage-dependent L-type calcium channel subunit beta-2, CAB2, Calcium channel voltage-dependent subunit beta 2, Lambert-Eaton myasthenic syndrome antigen B, MYSB, CACNB2, CACNLB2, MYSB
Tested Applications
WB
Protein ID
145559447
Physical Properties
Liquid

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