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CACNB3 Antibody

CAT: 0223-59-240Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-59-240Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The beta subunit of voltage-dependent calcium channels contributes to the function of the calcium channel by increasing peak calcium current, shifting the voltage dependencies of activation and inactivation, modulating G protein inhibition and controlling the alpha-1 subunit membrane targeting.
NCBI Gene ID
784
Swiss Prot
P54284
Accession Number
P54284
Host
Rabbit
Reactivity
Human
Immunogen
This CACNB3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 407-434 amino acids from the C-terminal region of human CACNB3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rabbit, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
55 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
CACNB3
NCBI Official Name
Voltage-dependent L-type calcium channel subunit beta-3
NCBI Organism
Homo sapiens
Background Reference 01
Zhang, Y., et al. J. Biol. Chem. 285 (4) :2527-2536 (2010)
Background Reference 02
Bernardo, J.F., et al. Can. J. Physiol. Pharmacol. 87 (7) :522-530 (2009)
Background Reference 03
Voss, M., et al. BMC Immunol. 10, 53 (2009) :
Background Reference 04
Rikova, K., et al. Cell 131 (6) :1190-1203 (2007)
Other Product Names
Voltage-dependent L-type calcium channel subunit beta-3, CAB3, Calcium channel voltage-dependent subunit beta 3, CACNB3, CACNLB3
Tested Applications
WB
Protein ID
1705683
Physical Properties
Liquid