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PRKRIR Antibody

CAT: 0223-58-044Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-044Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Upstream regulator of interferon-induced serine/threonine protein kinase R (PKR) . May block the PKR-inhibitory function of P58IPK, resulting in restoration of kinase activity and suppression of cell growth.
NCBI Gene ID
5612
Swiss Prot
O43422
Accession Number
O43422
Host
Rabbit
Reactivity
Human
Immunogen
This PRKRIR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 102-130 amino acids from the N-terminal region of human PRKRIR.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
88 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PRKRIR
NCBI Official Name
52 kDa repressor of the inhibitor of the protein kinase
NCBI Organism
Homo sapiens
Background Reference 01
Silva, L.K., et al. Eur. J. Hum. Genet. 18 (11) :1221-1227 (2010)
Background Reference 02
Johnatty, S.E., et al. PLoS Genet. (7), E1001016 (2010) :
Background Reference 03
Lee, J.H., et al. KoreanGastroenterol 42 (6) :484-495 (2003)
Background Reference 04
Lin, Y., et al. J. Biol. Chem. 277 (50) :47991-48001 (2002)
Other Product Names
52 kDa repressor of the inhibitor of the protein kinase, p52rIPK, 58 kDa interferon-induced protein kinase-interacting protein, p58IPK-interacting protein, Death-associated protein 4, THAP domain-containing protein 0, PRKRIR, DAP4, P52RIPK, THAP0
Tested Applications
WB
Physical Properties
Liquid

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