LALBA Antibody

• Background:

  This gene encodes alpha-lactalbumin, a principal protein of milk. Alpha-lactalbumin forms the regulatory subunit of the lactose synthase (LS) heterodimer and beta 1,4-galactosyltransferase (beta4Gal-T1) forms the catalytic component. Together, these proteins enable LS to produce lactose by transfering galactose moieties to glucose. As a monomer, alpha-lactalbumin strongly binds calcium and zinc ions and may possess bactericidal or antitumor activity. A folding variant of alpha-lactalbumin, called HAMLET, likely induces apoptosis in tumor and immature cells.

• NCBI Gene ID:

  3906

• Swiss Prot:

  P00709

• Accession Number:

  P00709

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This LALBA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the Central region of human LALBA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Immunology

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  16 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  LALBA

• NCBI Official Name:

  Alpha-lactalbumin

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tolin, S., et al. FEBS J. 277 (1) :163-173 (2010)

• Background Reference 02:

  Rosner, H.I., et al. J. Mol. Biol. 394 (2) :351-362 (2009)

• Background Reference 03:

  Wang, J., et al. J. Dairy Sci. 91 (12) :4466-4476 (2008)

• Background Reference 04:

  Ramboarina, S., et al. J. Am. Chem. Soc. 130 (46) :15318-15326 (2008)

• Other Product Names:

  Alpha-lactalbumin, Lactose synthase B protein, Lysozyme-like protein 7, LALBA, LYZL7

• Tested Applications:

  WB, IHC-P

• Protein ID:

  126001

• Physical Properties:

  Liquid