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HBEGF Antibody

CAT: 0223-58-020Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-020Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
HBEGF may be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for smooth muscle cells than EGF. Also acts as a diphtheria toxin receptor.
NCBI Gene ID
1839
Swiss Prot
Q99075
Accession Number
Q99075
Host
Rabbit
Reactivity
Human
Immunogen
This HBEGF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 68-96 amino acids from the Central region of human HBEGF.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
23 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
HBEGF
NCBI Official Name
Proheparin-binding EGF-like growth factor
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Rahman, F.B., et al. Lab. Invest. 90 (7) :1033-1048 (2010)
Background Reference 03
Hamaoka, M., et al. J. Biochem. 148 (1) :55-69 (2010)
Background Reference 04
Smirnova, I.S., et al. Tsitologiia 52 (5) :357-363 (2010)
Other Product Names
Proheparin-binding EGF-like growth factor, Heparin-binding EGF-like growth factor, HB-EGF, HBEGF, Diphtheria toxin receptor, DT-R, HBEGF, DTR, DTS, HEGFL
Tested Applications
WB
Protein ID
544477
Physical Properties
Liquid

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