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CYSLTR1 Antibody

CAT: 0223-58-011Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-011Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.
NCBI Gene ID
10800
Swiss Prot
Q9Y271
Accession Number
Q9Y271
Host
Rabbit
Reactivity
Human
Immunogen
This CYSLTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human CYSLTR1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience, Growth Factors
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
39 kDa
Fragment
Rabbit Ig
Symbol
CYSLTR1
NCBI Official Name
Cysteinyl leukotriene receptor 1
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Boulay, M.E., et al. Prostaglandins Leukot. Essent. Fatty Acids 83 (1) :15-22 (2010)
Background Reference 03
Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)
Background Reference 04
Hasegawa, S., et al. Platelets 21 (4) :253-259 (2010)
Other Product Names
Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81, CYSLTR1, CYSLT1
Tested Applications
WB, IHC-P
Protein ID
20138087
Physical Properties
Liquid

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