CYSLTR1 Antibody

• Background :

  The cysteinyl leukotrienes LTC4, LTD4, and LTE4 are important mediators of human bronchial asthma. Pharmacologic studies have determined that cysteinyl leukotrienes activate at least 2 receptors, the protein encoded by this gene and CYSLTR2. This encoded receptor is a member of the superfamily of G protein-coupled receptors. Activation of this receptor by LTD4 results in contraction and proliferation of smooth muscle, oedema, eosinophil migration and damage to the mucus layer in the lung.

• NCBI Gene ID :

  10800

• Swiss Prot :

  Q9Y271

• Accession Number :

  Q9Y271

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This CYSLTR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 144-172 amino acids from the Central region of human CYSLTR1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Neuroscience, Growth Factors

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  39 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  CYSLTR1

• NCBI Official Name :

  Cysteinyl leukotriene receptor 1

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)

• Background Reference 02 :

  Boulay, M.E., et al. Prostaglandins Leukot. Essent. Fatty Acids 83 (1) :15-22 (2010)

• Background Reference 03 :

  Schuurhof, A., et al. Pediatr. Pulmonol. 45 (6) :608-613 (2010)

• Background Reference 04 :

  Hasegawa, S., et al. Platelets 21 (4) :253-259 (2010)

• Other Product Names :

  Cysteinyl leukotriene receptor 1, CysLTR1, Cysteinyl leukotriene D4 receptor, LTD4 receptor, G-protein coupled receptor HG55, HMTMF81, CYSLTR1, CYSLT1

• Tested Applications :

  WB, IHC-P

• Protein ID :

  20138087

• Physical Properties :

  Liquid