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PTPN14 Antibody

CAT: 0223-58-009Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-58-009Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.
NCBI Gene ID
5784
Swiss Prot
Q15678
Accession Number
Q15678
Host
Rabbit
Reactivity
Mouse
Immunogen
This PTPN14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 862-890 amino acids from the C-terminal region of human PTPN14.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
135 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
PTPN14
NCBI Official Name
Tyrosine-protein phosphatase non-receptor type 14
NCBI Organism
Homo sapiens
Background Reference 01
Au, A.C., et al. Am. J. Hum. Genet. 87 (3) :436-444 (2010)
Background Reference 02
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :
Background Reference 03
Wyatt, L., et al. Cell Cycle 7 (15) :2290-2295 (2008)
Background Reference 04
Matsuoka, S., et al. Science 316 (5828) :1160-1166 (2007)
Other Product Names
Tyrosine-protein phosphatase non-receptor type 14, Protein-tyrosine phosphatase pez, PTPN14, PEZ, PTPD2
Tested Applications
WB
Protein ID
209572662
Physical Properties
Liquid

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