BRF1 Antibody

CAT: 0223-57-998Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-998Size:400 µL
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Background
This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Two alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. Other transcript variants are possible, but their full-length natures have not been completely characterized. [provided by RefSeq].
NCBI Gene ID
2972
Swiss Prot
Q92994
Accession Number
Q92994
Host
Rabbit
Reactivity
Human
Immunogen
This BRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the Central region of human BRF1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Other
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
74 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
BRF1
NCBI Official Name
Transcription factor IIIB 90 kDa subunit
NCBI Organism
Homo sapiens
Background Reference 01
Haurie, V., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (9) :4176-4181 (2010)
Background Reference 02
Maitra, S., et al. RNA 14 (5) :950-959 (2008)
Background Reference 03
Leal, J.F., et al. Oncogene 27 (14) :1961-1970 (2008)
Background Reference 04
Yoo, N.K., et al. Cell. Microbiol. 10 (3) :583-592 (2008)
Other Product Names
Transcription factor IIIB 90 kDa subunit, TFIIIB90, hTFIIIB90, B-related factor 1, BRF-1, hBRF, TAF3B2, TATA box-binding protein-associated factor, RNA polymerase III, subunit 2, BRF1, BRF, GTF3B, TAF3B2, TAF3C
Tested Applications
WB
Protein ID
20455319
Physical Properties
Liquid

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