BRF1 Antibody

• Background :

  This gene encodes one of the three subunits of the RNA polymerase III transcription factor complex. This complex plays a central role in transcription initiation by RNA polymerase III on genes encoding tRNA, 5S rRNA, and other small structural RNAs. The gene product belongs to the TF2B family. Two alternatively spliced variants encoding different isoforms, that function at different promoters transcribed by RNA polymerase III, have been identified. Other transcript variants are possible, but their full-length natures have not been completely characterized. [provided by RefSeq].

• NCBI Gene ID :

  2972

• Swiss Prot :

  Q92994

• Accession Number :

  Q92994

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  This BRF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 314-342 amino acids from the Central region of human BRF1.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Other

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  74 kDa

• Fragment :

  Rabbit Ig

• Applications Notes :

  For WB starting dilution is: 1:1000

• Symbol :

  BRF1

• NCBI Official Name :

  Transcription factor IIIB 90 kDa subunit

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Haurie, V., et al. Proc. Natl. Acad. Sci. U.S.A. 107 (9) :4176-4181 (2010)

• Background Reference 02 :

  Maitra, S., et al. RNA 14 (5) :950-959 (2008)

• Background Reference 03 :

  Leal, J.F., et al. Oncogene 27 (14) :1961-1970 (2008)

• Background Reference 04 :

  Yoo, N.K., et al. Cell. Microbiol. 10 (3) :583-592 (2008)

• Other Product Names :

  Transcription factor IIIB 90 kDa subunit, TFIIIB90, hTFIIIB90, B-related factor 1, BRF-1, hBRF, TAF3B2, TATA box-binding protein-associated factor, RNA polymerase III, subunit 2, BRF1, BRF, GTF3B, TAF3B2, TAF3C

• Tested Applications :

  WB

• Protein ID :

  20455319

• Physical Properties :

  Liquid