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A2M Antibody

CAT: 0223-57-992Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-992Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits. [provided by RefSeq].
NCBI Gene ID
2
Swiss Prot
P01023
Accession Number
P01023
Host
Rabbit
Reactivity
Human
Immunogen
This A2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1162-1192 amino acids from the C-terminal region of human A2M.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cell Cycle
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
163 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
A2M
NCBI Official Name
Alpha-2-macroglobulin
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Bruno, E., et al. Neurosci. Lett. 482 (2) :112-116 (2010)
Background Reference 03
Nalpas, B., et al. Gut 59 (8) :1120-1126 (2010)
Background Reference 04
Song, H., et al. Neurosci. Lett. 479 (2) :143-145 (2010)
Other Product Names
Alpha-2-macroglobulin, Alpha-2-M, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 5, A2M, CPAMD5
Tested Applications
WB
Protein ID
308153640
Physical Properties
Liquid

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