VAMP3 Antibody

• Background :

  Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.

• NCBI Gene ID :

  9341

• Swiss Prot :

  Q15836

• Accession Number :

  Q15836

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Zebrafish

• Immunogen :

  This VAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the Central region of human VAMP3.

• Clonality :

  Polyclonal

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Cancer, Obesity, Neuroscience, Signal Transduction

• Purification :

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration :

  Batch dependent

• Homology :

  Predicted species reactivity based on immunogen sequence: Bovine, Rat, Monkey

• Buffer :

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight :

  11 kDa

• Fragment :

  Rabbit Ig

• Symbol :

  VAMP3

• NCBI Official Name :

  Vesicle-associated membrane protein 3

• NCBI Organism :

  Homo sapiens

• Background Reference 01 :

  Ban, H.J., et al. BMC Genet. 11, 26 (2010) :

• Background Reference 02 :

  Fader, C.M., et al. Biochim. Biophys. Acta 1793 (12) :1901-1916 (2009)

• Background Reference 03 :

  Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :

• Background Reference 04 :

  Vassilopoulos, S., et al. Science 324 (5931) :1192-1196 (2009)

• Other Product Names :

  Vesicle-associated membrane protein 3, VAMP-3, Cellubrevin, CEB, Synaptobrevin-3, VAMP3, SYB3

• Tested Applications :

  WB, IHC-P

• Protein ID :

  2501082

• Physical Properties :

  Liquid