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VAMP3 Antibody

CAT: 0223-57-894Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-894Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. Because of its high homology to other known VAMPs, its broad tissue distribution, and its subcellular localization, the protein encoded by this gene was shown to be the human equivalent of the rodent cellubrevin. In platelets the protein resides on a compartment that is not mobilized to the plasma membrane on calcium or thrombin stimulation.
NCBI Gene ID
9341
Swiss Prot
Q15836
Accession Number
Q15836
Host
Rabbit
Reactivity
Human, Mouse, Zebrafish
Immunogen
This VAMP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the Central region of human VAMP3.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat, Monkey
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
11 kDa
Fragment
Rabbit Ig
Symbol
VAMP3
NCBI Official Name
Vesicle-associated membrane protein 3
NCBI Organism
Homo sapiens
Background Reference 01
Ban, H.J., et al. BMC Genet. 11, 26 (2010) :
Background Reference 02
Fader, C.M., et al. Biochim. Biophys. Acta 1793 (12) :1901-1916 (2009)
Background Reference 03
Kean, M.J., et al. J. Cell. Sci. 122 (PT 22), 4089-4098 (2009) :
Background Reference 04
Vassilopoulos, S., et al. Science 324 (5931) :1192-1196 (2009)
Other Product Names
Vesicle-associated membrane protein 3, VAMP-3, Cellubrevin, CEB, Synaptobrevin-3, VAMP3, SYB3
Tested Applications
WB, IHC-P
Protein ID
2501082
Physical Properties
Liquid

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