VAMP2 Antibody

• Background:

  The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP) /synaptobrevin family. Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. This gene is thought to participate in neurotransmitter release at a step between docking and fusion. The protein forms a stable complex with syntaxin, synaptosomal-associated protein, 25 kD, and synaptotagmin. It also forms a distinct complex with synaptophysin. It is a likely candidate gene for familial infantile myasthenia (FIMG) because of its map location and because it encodes a synaptic vesicle protein of the type that has been implicated in the pathogenesis of FIMG.

• NCBI Gene ID:

  6844

• Swiss Prot:

  P63027

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VAMP2 (NP_055047.2) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Neuroscience, Signal Transduction

• Purification:

  Affinity purification

• Positive Control:

  22Rv1

• Concentration:

  Batch dependent

• Buffer:

  PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at -20˚ C. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  Observed: 16kDa

• Fragment:

  IgG

• Symbol:

  VAMP2

• Positive Control 2:

  Mouse brain

• Positive Control 3:

  Mouse lung

• Positive Control 4:

  Rat brain

• NCBI Official Name:

  Vesicle-associated membrane protein 2 (synaptobrevin 2)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  VAMP2, SYB2, Synaptobrevin 2, VAMP-2, Synaptobrevin-2

• Tested Applications:

  WB, IHC

• Physical Properties:

  Liquid