CSDA Antibody

• Background:

  CSDA binds to the GM-CSF promoter. Seems to act as a repressor. Binds also to full length mRNA and to short RNA sequences containing the consensus site 5'-UCCAUCA-3'. May have a role in translation repression (By similarity) .

• NCBI Gene ID:

  8531

• Swiss Prot:

  P16989

• Accession Number:

  P16989

• Host:

  Rabbit

• Reactivity:

  Human, Mouse

• Immunogen:

  This CSDA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 152-181 amino acids from the Central region of human CSDA.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  40 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  YBX3

• NCBI Official Name:

  Y-box-binding protein 3

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Lima, W.R., et al. J. Am. Soc. Nephrol. 21 (3) :478-488 (2010)

• Background Reference 02:

  Wang, G.R., et al. Acta Pharmacol. Sin. 30 (10) :1436-1442 (2009)

• Background Reference 03:

  Sharpe Elles, L.M., et al. Nucleic Acids Res. 37 (19) :6503-6514 (2009)

• Background Reference 04:

  Buchert, M., et al. Gastroenterology 137 (1) :156-164 (2009)

• Other Product Names:

  Y-box-binding protein 3, Cold shock domain-containing protein A, DNA-binding protein A, Single-strand DNA-binding protein NF-GMB, YBX3, CSDA, DBPA

• Tested Applications:

  WB

• Protein ID:

  97536050

• Physical Properties:

  Liquid