BACH1 Antibody

• Background:

  This gene encodes a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip) . The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene.

• NCBI Gene ID:

  571

• Swiss Prot:

  O14867

• Accession Number:

  O14867

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This BACH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 670-698 amino acids from the C-terminal region of human BACH1.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Other

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  82 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  BACH1

• NCBI Official Name:

  Transcription regulator protein BACH1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Miyazaki, T., et al. Cancer Sci. 101 (6) :1409-1416 (2010)

• Background Reference 02:

  Hou, W., et al. Hepatology 51 (5) :1494-1504 (2010)

• Background Reference 03:

  Gong, Z., et al. Mol. Cell 37 (3) :438-446 (2010)

• Background Reference 04:

  Zhong, J.L., et al. Free Radic. Biol. Med. 48 (2) :196-206 (2010)

• Other Product Names:

  Transcription regulator protein BACH1, BTB and CNC homolog 1, HA2303, BACH1

• Tested Applications:

  WB

• Physical Properties:

  Liquid