LRP5 Antibody

CAT: 0223-57-888Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-888Size:400 µL
Selected
PRICE
AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Background
This gene encodes a transmembrane low-density lipoprotein receptor that binds and internalizes ligands in the process of receptor-mediated endocytosis. This protein also acts as a co-receptor with Frizzled protein family members for transducing signals by Wnt proteins and was originally cloned on the basis of its association with type 1 diabetes mellitus in humans. This protein plays a key role in skeletal homeostasis and many bone density related diseases are caused by mutations in this gene. Mutations in this gene also cause familial exudative vitreoretinopathy.
NCBI Gene ID
4041
Swiss Prot
O75197
Accession Number
O75197
Host
Rabbit
Reactivity
Mouse
Immunogen
This LRP5 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1163-1190 amino acids from the C-terminal region of human LRP5.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Obesity, Neuroscience, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
179 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
LRP5
NCBI Official Name
Low-density lipoprotein receptor-related protein 5
NCBI Organism
Homo sapiens
Background Reference 01
Bailey, S.D., et al. Diabetes Care 33 (10) :2250-2253 (2010)
Background Reference 02
Lee, D.Y., et al. Menopause 17 (5) :1064-1070 (2010)
Background Reference 03
Liu, J.M., et al. J. Clin. Endocrinol. Metab. 95 (9), E112-E120 (2010) :
Background Reference 04
Paternoster, L., et al. J. Clin. Endocrinol. Metab. 95 (8) :3940-3948 (2010)
Other Product Names
Low-density lipoprotein receptor-related protein 5, LRP-5, LRP5, LR3, LRP7
Tested Applications
WB
Physical Properties
Liquid

Related Products

CatalogName
45-846PLRP5 Peptide
15-144LRP6 Antibody
27-188LRP1 Antibody
43-685LRP1 Antibody
43-673LRP1 Antibody
15-516LRP1 Antibody
26-001LRP8 Antibody
62-144LRP2 Antibody
62-147LRP6 Antibody
13-704LRP8 Antibody

Alternative Products

CatalogName
F40130-0.08MLLRP5 Antibody

Popular Products