LRP8 Antibody

CAT: 0223-13-704Size: 100 µLDry Ice: NoHazardous: No
CAT#:0223-13-704Size:100 µL
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Background
This gene encodes a member of the low density lipoprotein receptor (LDLR) family. Low density lipoprotein receptors are cell surface proteins that play roles in both signal transduction and receptor-mediated endocytosis of specific ligands for lysosomal degradation. The encoded protein plays a critical role in the migration of neurons during development by mediating Reelin signaling, and also functions as a receptor for the cholesterol transport protein apolipoprotein E. Expression of this gene may be a marker for major depressive disorder. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
NCBI Gene ID
7804
Swiss Prot
Q14114
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 900 to the C-terminus of human LRP8 (NP_004622.2) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Neuroscience, Obesity, Signal Transduction
Purification
Affinity purification
Positive Control
SH-SY5Y
Concentration
Batch dependent
Buffer
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at -20˚ C. Avoid freeze / thaw cycles.
Calculated Molecular Weight
Observed: 105-120kDa
Fragment
IgG
Applications Notes
WB: 1:500 - 1:2000
Symbol
LRP8
Positive Control 2
Rat testis
NCBI Official Name
Low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
NCBI Organism
Homo sapiens
Other Product Names
LRP8, APOER2, HSZ75190, MCI1, LRP-8, RP5-1024G6.8
Tested Applications
WB
Physical Properties
Liquid

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