AIP Antibody

• Background:

  The protein encoded by this gene is a receptor for aryl hydrocarbons and a ligand-activated transcription factor. The encoded protein is found in the cytoplasm as part of a multiprotein complex, but upon binding of ligand is transported to the nucleus. This protein can regulate the expression of many xenobiotic metabolizing enzymes. Also, the encoded protein can bind specifically to and inhibit the activity of hepatitis B virus.

• NCBI Gene ID:

  9049

• Swiss Prot:

  O00170

• Accession Number:

  O00170

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This AIP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 293-321 amino acids from the C-terminal region of human AIP.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Neuroscience

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Rat

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  38 kDa

• Fragment:

  Rabbit Ig

• Symbol:

  AIP

• NCBI Official Name:

  AH receptor-interacting protein

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Daly, A.F., et al. J. Clin. Endocrinol. Metab. 95 (11), E373-E383 (2010) :

• Background Reference 02:

  Stratakis, C.A., et al. Clin. Genet. 78 (5) :457-463 (2010)

• Background Reference 03:

  Occhi, G., et al. Eur. J. Endocrinol. 163 (3) :369-376 (2010)

• Background Reference 04:

  Igreja, S., et al. Hum. Mutat. 31 (8) :950-960 (2010)

• Other Product Names:

  AH receptor-interacting protein, AIP, Aryl-hydrocarbon receptor-interacting protein, HBV X-associated protein 2, XAP-2, Immunophilin homolog ARA9, AIP, XAP2

• Tested Applications:

  WB, IHC-P

• Physical Properties:

  Liquid