P2RY12 Antibody

• Background:

  P2RY12 belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders.The product of this gene belongs to the family of G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor is involved in platelets aggregation, and is a potential target for the treatment of thromboembolisms and other clotting disorders. Two transcript variants encoding the same isoform have been identified for this gene.

• NCBI Gene ID:

  5028

• Swiss Prot:

  P47900

• Accession Number:

  NP_795345

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Antibody produced in rabbits immunized with a synthetic peptide corresponding a region of human P2RY12.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Membrane, Signal Transduction

• Purification:

  Antibody is purified by peptide affinity chromatography method.

• Positive Control:

  Cat. No. XBL-10413 - Fetal Skeletal Muscle Tissue Lysate

• Concentration:

  Batch dependent

• Buffer:

  Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  For short periods of storage (days) store at 4˚ C. For longer periods of storage, store P2RY12 antibody at -20˚ C. As with any antibody avoid repeat freeze-thaw cycles.

• Calculated Molecular Weight:

  39 kDa

• Applications Notes:

  P2RY12 antibody can be used for detection of P2RY12 by ELISA at 1:312500. P2RY12 antibody can be used for detection of P2RY12 by western blot at 1 μ g/mL, and HRP conjugated secondary antibody should be diluted 1:50,000 - 100,000.

• Symbol:

  P2RY1

• NCBI Official Name:

  Purinergic receptor P2Y, G-protein coupled, 1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Staritz, P., (er) Int. J. Cardiol. (2008) In press.

• Other Product Names:

  P2RY12, ADPG-R, HORK3, P2T (AC), P2Y (AC), P2Y (ADP), P2Y (cyc), P2Y12, SP1999, P2Y1

• Tested Applications:

  ELISA, WB

• Protein ID:

  29029605

• Physical Properties:

  Liquid