ARC Antibody

CAT: 0223-57-806Size: 400 µLDry Ice: NoHazardous: No
CAT#:0223-57-806Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
ARCis required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors (By similarity) .
NCBI Gene ID
23237
Swiss Prot
Q7LC44
Accession Number
Q7LC44
Host
Rabbit
Reactivity
Human
Immunogen
This ARC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 37-66 amino acids from the N-terminal region of human ARC.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Neuroscience
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Mouse, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
45 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ARC
NCBI Official Name
Activity-regulated cytoskeleton-associated protein
NCBI Organism
Homo sapiens
Background Reference 01
Bloomer, W.A., et al. Brain Res. 1153, 20-33 (2007) :
Background Reference 02
Dynes, J.L., et al. J. Comp. Neurol. 500 (3) :433-447 (2007)
Background Reference 03
Haug, K., et al. Mol. Cell. Probes 14 (4) :255-260 (2000)
Background Reference 04
Kremerskothen, J., et al. Chromosome Res. (7), 655 (2000) :
Other Product Names
Activity-regulated cytoskeleton-associated protein, ARC/ARG31, Activity-regulated gene 31 protein homolog, Arg31, ARC {ECO:0000312|EMBL:AAG337051}
Tested Applications
WB
Protein ID
74738627
Physical Properties
Liquid

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