WASF2 Antibody

• Background:

  This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X.

• NCBI Gene ID:

  10163

• Swiss Prot:

  Q9Y6W5

• Accession Number:

  Q9Y6W5

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This WASF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the Central region of human WASF2.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Homology:

  Predicted species reactivity based on immunogen sequence: Bovine, Mouse

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  54 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  WASF2

• NCBI Official Name:

  Wiskott-Aldrich syndrome protein family member 2

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Takahashi, K., et al. Cell. Signal. 22 (3) :510-518 (2010)

• Background Reference 02:

  Lebensohn, A.M., et al. Mol. Cell 36 (3) :512-524 (2009)

• Background Reference 03:

  Cai, X., et al. Lung Cancer 65 (3) :299-305 (2009)

• Background Reference 04:

  Morimura, S., et al. Biochem. Biophys. Res. Commun. 382 (3) :614-619 (2009)

• Other Product Names:

  Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, Protein WAVE-2, Verprolin homology domain-containing protein 2, WASF2, WAVE2

• Tested Applications:

  WB

• Protein ID:

  59800456

• Physical Properties:

  Liquid