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WASF2 Antibody

CAT: 0223-57-800Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-800Size:400 µL
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Background
This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X.
NCBI Gene ID
10163
Swiss Prot
Q9Y6W5
Accession Number
Q9Y6W5
Host
Rabbit
Reactivity
Human
Immunogen
This WASF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 162-190 amino acids from the Central region of human WASF2.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Cancer, Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Mouse
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
54 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
WASF2
NCBI Official Name
Wiskott-Aldrich syndrome protein family member 2
NCBI Organism
Homo sapiens
Background Reference 01
Takahashi, K., et al. Cell. Signal. 22 (3) :510-518 (2010)
Background Reference 02
Lebensohn, A.M., et al. Mol. Cell 36 (3) :512-524 (2009)
Background Reference 03
Cai, X., et al. Lung Cancer 65 (3) :299-305 (2009)
Background Reference 04
Morimura, S., et al. Biochem. Biophys. Res. Commun. 382 (3) :614-619 (2009)
Other Product Names
Wiskott-Aldrich syndrome protein family member 2, WASP family protein member 2, Protein WAVE-2, Verprolin homology domain-containing protein 2, WASF2, WAVE2
Tested Applications
WB
Protein ID
59800456
Physical Properties
Liquid

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