AATK Antibody

• Background:

  The protein encoded by this gene contains a tyrosine kinase domain at the N-terminus and a proline-rich domain at the C-terminus. This gene is induced during apoptosis, and expression of this gene may be a necessary pre-requisite for the induction of growth arrest and/or apoptosis of myeloid precursor cells. This gene has been shown to produce neuronal differentiation in a neuroblastoma cell line.

• NCBI Gene ID:

  9625

• Swiss Prot:

  Q6ZMQ8

• Accession Number:

  Q6ZMQ8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  This AATK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 46-74 amino acids from the N-terminal region of human AATK.

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cell Cycle, Neuroscience, Signal Transduction

• Purification:

  This antibody is purified through a protein A column, followed by peptide affinity purification.

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS with 0.09% (W/V) sodium azide.

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

• Calculated Molecular Weight:

  145 kDa

• Fragment:

  Rabbit Ig

• Applications Notes:

  For WB starting dilution is: 1:1000

• Symbol:

  AATK

• NCBI Official Name:

  Serine/threonine-protein kinase LMTK1

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tomomura, M., et al. Neurobiology 148 (2) :510-521 (2007)

• Background Reference 02:

  Lee, S., et al. Oncol. Rep. 16 (4) :747-754 (2006)

• Background Reference 03:

  Honma, N., et al. Biochem. Biophys. Res. Commun. 310 (2) :398-404 (2003)

• Background Reference 04:

  Tomomura, M., et al. Brain Res. Mol. Brain Res. 112 (1-2), 103-112 (2003) :

• Other Product Names:

  Serine/threonine-protein kinase LMTK1, Apoptosis-associated tyrosine kinase, AATYK, Brain apoptosis-associated tyrosine kinase, CDK5-binding protein, Lemur tyrosine kinase 1, p35-binding protein, p35BP, AATK, AATYK, KIAA0641, LMR1, LMTK1

• Tested Applications:

  WB

• Protein ID:

  114149222

• Physical Properties:

  Liquid