Products for Research Use Only

ASAP1 Antibody

CAT: 0223-57-774Size: 400 µLDry Ice: NoHazardous: No
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CAT#:0223-57-774Size:400 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Possesses phosphatidylinositol 4,5-biphosphate-dependent GTPase-activating protein activity for ARF1 (ADP ribosylation factor 1) and ARF5 and a lesser activity towards ARF6. May coordinate membrane trafficking with cell growth or actin cytoskeleton remodeling by binding to both SRC and PIP2. May function as a signal transduction protein involved in the differentiation of fibroblasts into adipocytes and possibly other cell types (By similarity) .
NCBI Gene ID
50807
Swiss Prot
Q9ULH1
Accession Number
Q9ULH1
Host
Rabbit
Reactivity
Mouse
Immunogen
This ASAP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-388 amino acids from the Central region of human ASAP1.
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies
Field of Research
Signal Transduction
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Batch dependent
Homology
Predicted species reactivity based on immunogen sequence: Bovine, Rat
Buffer
Supplied in PBS with 0.09% (W/V) sodium azide.
Modification
None
Shipping Conditions
Blue Ice
Storage Conditions
Store at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Calculated Molecular Weight
125 kDa
Fragment
Rabbit Ig
Applications Notes
For WB starting dilution is: 1:1000
Symbol
ASAP1
NCBI Official Name
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1
NCBI Organism
Homo sapiens
Background Reference 01
Muller, T., et al. Oncogene 29 (16) :2393-2403 (2010)
Background Reference 02
Nat. Genet. 41 (7) :824-828 (2009)
Background Reference 03
Jian, X., et al. J. Biol. Chem. 284 (3) :1652-1663 (2009)
Background Reference 04
Inoue, H., et al. Mol. Biol. Cell 19 (10) :4224-4237 (2008)
Other Product Names
Arf-GAP with SH3 domain, ANK repeat and PH domain-containing protein 1, 130 kDa phosphatidylinositol 4,5-bisphosphate-dependent ARF1 GTPase-activating protein, ADP-ribosylation factor-directed GTPase-activating protein 1, ARF GTPase-activating protein 1, Development and differentiation-enhancing factor 1, DEF-1, Differentiation-enhancing factor 1, PIP2-dependent ARF1 GAP, ASAP1, DDEF1, KIAA1249
Tested Applications
WB
Protein ID
296439459
Physical Properties
Liquid